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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PHF2
All Species:
8.79
Human Site:
Y677
Identified Species:
21.48
UniProt:
O75151
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75151
NP_005383.3
1096
120775
Y677
P
K
P
V
R
D
E
Y
E
Y
V
S
D
D
G
Chimpanzee
Pan troglodytes
XP_521077
902
100718
I504
L
P
D
H
E
D
E
I
P
E
T
V
R
T
V
Rhesus Macaque
Macaca mulatta
XP_001109325
941
106786
P543
L
K
R
L
E
M
C
P
W
E
E
D
I
L
S
Dog
Lupus familis
XP_541324
1207
131875
Y771
P
Q
P
V
R
D
E
Y
E
Y
V
S
D
D
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9WTU0
1096
120795
Y673
A
K
P
V
R
D
E
Y
E
Y
V
S
D
D
G
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508529
1024
113352
E626
E
F
D
L
D
S
E
E
D
L
Q
I
D
E
T
Chicken
Gallus gallus
XP_414324
1061
118324
F660
T
Q
L
N
T
S
V
F
G
S
L
Q
N
F
K
Frog
Xenopus laevis
Q640I9
1259
144035
L782
D
P
S
V
R
K
R
L
K
L
V
K
E
E
K
Zebra Danio
Brachydanio rerio
P0CF52
577
66988
V179
K
M
K
L
K
A
F
V
K
Y
Y
Y
S
P
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VHH9
1345
146160
F856
P
V
G
Q
Y
N
D
F
V
F
T
S
E
S
E
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
37.5
37.5
82
N.A.
93.8
N.A.
N.A.
50.3
80.1
22.5
30.1
N.A.
23.1
N.A.
N.A.
N.A.
Protein Similarity:
100
51.5
52.8
85.5
N.A.
95.9
N.A.
N.A.
64.9
87.8
38.2
38.7
N.A.
37.8
N.A.
N.A.
N.A.
P-Site Identity:
100
13.3
6.6
93.3
N.A.
93.3
N.A.
N.A.
13.3
0
20
6.6
N.A.
13.3
N.A.
N.A.
N.A.
P-Site Similarity:
100
13.3
13.3
100
N.A.
93.3
N.A.
N.A.
33.3
26.6
40
26.6
N.A.
46.6
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% C
% Asp:
10
0
20
0
10
40
10
0
10
0
0
10
40
30
0
% D
% Glu:
10
0
0
0
20
0
50
10
30
20
10
0
20
20
10
% E
% Phe:
0
10
0
0
0
0
10
20
0
10
0
0
0
10
0
% F
% Gly:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
30
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
10
10
0
0
% I
% Lys:
10
30
10
0
10
10
0
0
20
0
0
10
0
0
20
% K
% Leu:
20
0
10
30
0
0
0
10
0
20
10
0
0
10
0
% L
% Met:
0
10
0
0
0
10
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
10
0
10
0
0
0
0
0
0
10
0
0
% N
% Pro:
30
20
30
0
0
0
0
10
10
0
0
0
0
10
0
% P
% Gln:
0
20
0
10
0
0
0
0
0
0
10
10
0
0
10
% Q
% Arg:
0
0
10
0
40
0
10
0
0
0
0
0
10
0
0
% R
% Ser:
0
0
10
0
0
20
0
0
0
10
0
40
10
10
10
% S
% Thr:
10
0
0
0
10
0
0
0
0
0
20
0
0
10
10
% T
% Val:
0
10
0
40
0
0
10
10
10
0
40
10
0
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
30
0
40
10
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _